Chemicals

Dacomitinib (PF299804,PF-00299804) can inhibit ErbB1, ErbB2, and ErbB4. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of the ...

CI-1033 (Canertinib) can inhibit EGFR and ErbB2 with IC50 of 1.5 nM and 9.0 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of ...

Palomid 529 inhibits both VEGF-driven and bFGF-driven endothelial cell proliferation with IC50 of 20 nM and 30 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They ...

Temsirolimus (Torisel) can inhibit mTOR with IC50 of 1.76 uM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of the enzyme and ...

NU7441 (KU-57788) can inhibit DNA-PK with IC50 of 14 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of the enzyme and ...

CAL-101 (GS-1101) can inhibit p110-delta with IC50 of 2.5 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of the enzyme and ...

BKM120 (NVP-BKM120) can inhibit p110-alpha, p110-beta, p110-delta and p110-gamma with IC50 of 52 nM, 166 nM, 166 nM and 262 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal ...

Everolimus (RAD001) can inhibit FKBP12 with IC50 of 1.6-2.4 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of the enzyme and ...

Rapamycin(Sirolimus) can inhibit mTOR with IC50 of 0.1 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of the enzyme and ...

Deforolimus (Ridaforolimus, AP23573, MK-8669) can inhibit mTOR with IC50 of 0.2 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action ...