Chemicals

AZD8055 can inhibit mTOR with IC50 of 0.8 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of the enzyme and consequently slow ...

GSK690693 can inhibit akt1, akt2 and akt3 with IC50 of 2 nM, 13 nM, and 9 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of the ...

As an ATP-competitive inhibitor, AT7867 can potently Akt1, Akt2, Akt3 and S6K with IC50 of 32 nM, 17 nM, 47 nM and 85 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal ...

As a dual inhibitor of mTOR/PI3k, XL765 shows inhibition to mTOR, p110alpha, p110beta, p110gamma and p110delta with IC50 of 157 nM, 39 nM, 113 nM, 9 nM and 43 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to ...

PI-103 can inhibit p110-alpha, p110-beta, p110-delta, p110-gamma, mTORC1, mTORC2, DNA-PK and PI3KC2-beta with IC50 of 8 nM, 88 nM, 48 nM, 150 nM, 20 nM, 83 nM, 2 nM and 20 nM. Enzyme inhibitors are molecules that interact in certain ways with the ...

Perifosine can inhibit Akt with IC50 og 4.7 uM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of the enzyme and consequently slow ...

As a selective inhibitor, BX912 can potently inhibit PDK1 with IC50 of 12 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic action of the ...

PIK-90 can inhibit PI3Kalpha, PI3Kbeta, PI3Kdelta and PI3Kgamma with IC50 of 11 nM, 350 nM, 58 nM and 18 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can ...

WAY-600 is a potent, ATP-competitive and selective inhibitor of mTOR with IC50 of 9 nM. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from functioning in a normal manner. They can alter the catalytic ...

CP-466722, a nontoxic compound, is a ATM protein kinase inhibitor and shows no inhibition to PI3K, PI3K-like protein kinases or Abl kinase in cells. Enzyme inhibitors are molecules that interact in certain ways with the enzyme to prevent it from ...